A Case Study in Globalized Agribusiness Ethics: An Herbicide in the Spotlight

Jenita Thinakaran, C. Chinnusamy, Mark Wm Cawman


This case study considers the growth, industrialization, and globalization of agribusiness in feeding the world, and the efficiencies sought through various innovations, especially pesticides.  A particular herbicide (a subset of a pesticide) has significant ethical dilemmas, misinformation, disinformation, and possibly big business bias – all surrounding the debate on the continuance of use and potential collateral safety issues.  This case considers Corporate Social Responsibility and ethics as well as the tensions between efficiency and collateral issues in business decisions.  There are scientific reports that can support various conclusions and ongoing litigations use these in support of rulings that also have gone both ways.  This continues to be a dynamic issue as science and court rulings occur, but this case study is of interest and significance to the business, international business, agribusiness, and agronomy fields of study as typical to decisions various stakeholders face.

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American Chemical Council. (2021). Glyphosate and autism: Back to a fake news story (English Translation). Campaign for Accuracy in Public Health Research. Retrieved October 31, 2021, from https://campaignforaccuracyinpublichealthresearch.com/glyphosate-and-autism-back-to-a-fake-news-story-english-translation/

Baer, K., & Marcel, B. (2014). Glyphosate. In Encyclopedia of toxicology (pp. 767–769). Elsevier. https://doi.org/10.1016/b978-0-12-386454-3.00148-2

Baum Hedlund Law. (2021, August). Where is glyphosate banned? Monsanto Roundup Lawsuit. Retrieved October 31, 2021, from https://www.baumhedlundlaw.com/toxic-tort-law/monsanto-roundup-lawsuit/where-is-glyphosate-banned-/

Bayer. (n.d.-a). Benefits and safety of glyphosate. Cropscience.bayer.com. https://www.cropscience.bayer.com/sites/cropscience/files/inline-files/Glyphosate%20Benefits%20and%20Safety%20booklet.pdf

Bayer. (n.d.-b). Shaping agriculture. Cropscience.Bayer.com. https://www.cropscience.bayer.com/innovations/crop-protection/herbicides

Bellon, T. (2018, August 10). Monsanto ordered to pay $289 million in world's first Roundup cancer trial. Reuters. https://www.reuters.com/article/us-monsanto-cancer-lawsuit-idUSKBN1KV2HB

Benbrook, C. M. (2016). Trends in glyphosate herbicide use in the united states and globally. Environmental Sciences Europe, 28(1). https://doi.org/10.1186/s12302-016-0070-0

Benbrook, C. M. (2019). How did the us EPA and IARC reach diametrically opposed conclusions on the genotoxicity of glyphosate-based herbicides? Environmental Sciences Europe, 31(1). https://doi.org/10.1186/s12302-018-0184-7

Big Green Purse. (2020). The 7 most important reasons to avoid GMOs. http://biggreenpurse.com/the-7-most-important-reasons-to-avoid-gmos/

Brown, K., Stephenson, D. O., Gueltig, B., & Willis, J. (2019, November 1). 10 things you should know about glyphosate. LSU AgCenter Articles. https://www.lsuagcenter.com/profiles/aiverson/articles/page1573150527569

Bus, J. S. (2015). Analysis of moms across America report suggesting bioaccumulation of glyphosate in US. mother's breast milk: Implausibility based on inconsistency with available body of glyphosate animal toxicokinetic, human biomonitoring, and physico-chemical data. Regulatory Toxicology and Pharmacology, 73(3), 758–764. https://doi.org/10.1016/j.yrtph.2015.10.022

Carlson Law Firm. (2021, February 10). Which Countries and U.S. States are Banning Roundup? The Carlson Law Firm. Retrieved October 31, 2021, from https://www.carlsonattorneys.com/news-and-update/banning-roundup

Clark, D. (n.d.). How to be healthy naturally - Views of a research scientist | Glyphosate toxicity summary data. HerbScientist.com. https://herbscientist.com/glyphosate-toxicity-summary-data/

Cressey, D. (2015). Widely used herbicide linked to cancer. Nature. https://doi.org/10.1038/nature.2015.17181

Cuhra, M. (2015). Review of GMO safety assessment studies: Glyphosate residues in roundup ready crops is an ignored issue. Environmental Sciences Europe, 27(1). https://doi.org/10.1186/s12302-015-0052-7

Department of Agriculture - Government of Manipur. (n.d.). The insecticides act, 1968. Agrimanipur. http://www.agrimanipur.gov.in/the-insecticides-act-1968/

Directorate of Plant Protection, Quarantine and Storage. (2021). [various descriptions of glyphosate use]. http://ppqs.gov.in/. http://ppqs.gov.in/

Dukeshire, S. (2013). Concentration, consolidation, and control: How big business dominates the food system [Book Review of “Foodopoly"]. Journal of Agriculture, Food Systems, and Community Development, 4(1), 171–173. https://doi.org/10.5304/jafscd.2013.041.010

Environmental Protection Agency. (September 12, 2016). Glyphosate issue paper: Evaluation of carcinogenic potential [Issue Paper]. EPA - EPA’s Office of Pesticide Programs. https://www.epa.gov/sites/default/files/2016-09/documents/glyphosate_issue_paper_evaluation_of_carcincogenic_potential.pdf

European Chemicals Agency. (2017). Glyphosate not classified as a carcinogen by ECHA (ECHA/PR/17/06). ECHA (An Agency of the European Union). https://echa.europa.eu/-/glyphosate-not-classified-as-a-carcinogen-by-echa

European Commission. (n.d.). Status of glyphosate in the EU. https://ec.europa.eu/food/plants/pesticides/approval-active-substances/renewal-approval/glyphosate_en

Federation of Indian Chambers of Commerce & Industry. (2015). Knowledge paper on safer and judicious use of crop protection chemicals and applications of green chemistries (Industry Reports, Analysis by Tata Strategic) [Report]. FICCI. https://ficci.in/spdocument/20541/Kowledge-Paper-chem.pdf

Friedmann, H. (1991). Changes in the international division of labor: Agri-food complexes and export agriculture. In W. H. Friedland, L. Busch, F. H. Buttel, & A. P. Rudy (Eds.), Towards a new political economy of agriculture (1st ed.). Routledge. https://doi.org/10.4324/9780429269493

Global Agriculture. (n.d.). Global Agriculture. https://www.globalagriculture.org/

Gonzales, R. (2019, May 13). California jury awards $2 Billion to couple in Roundup weed killer cancer trial. Capradio (NPR). Retrieved November 7, 2021, from https://www.capradio.org/news/npr/story/?storyid=723056453

Google Dictionary. (n.d.). Pesticide. Retrieved October 30, 2021, from https://www.google.com/search?q=pesticides+definition&oq=pesticides&aqs=chrome.1.69i57j0i131i433i512j0i512l7j0i457i512.4161j0j15&sourceid=chrome&ie=UTF-8

Gronau, I. (2017, September 16). No-tilling tames slopes, makes tough soils productive. No-Till Farmer: Crop Protection, Soil Health, Water Management. https://www.no-tillfarmer.com/articles/7029-no-tilling-tames-slopes-makes-tough-soils-productive?v=preview

Guyton, K. Z., Loomis, D., Grosse, Y., El Ghissassi, F., Benbrahim-Tallaa, L., Guha, N., Scoccianti, C., Mattock, H., & Straif, K. (2015). Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate. The Lancet Oncology, 16(5), 490–491. https://doi.org/10.1016/s1470-2045(15)70134-8

Henderson, A. M., Gervais, J. A., Luukinen, B., Buhl, K., Stone, D., Cross, A., & Jenkins, J. (2010). Glyphosate general fact sheet [Data set]. National Pesticide Information Center, Oregon State University Extension Services. http://npic.orst.edu/factsheets/glyphogen.html

Hoss, N. E., Al-Khatib, K., Peterson, D. E., & Loughin, T. M. (2003). Efficacy of Glyphosate, Glufosinate, and Imazethapyr on Selected Weed Species. Weed Science, 5(1), 110–117. https://www.jstor.org/stable/4046633

Hutchison, A., & Stuhl, A. (1996, September 4). "Roundup Ready": The first widely used genetically modified crop. Environment & Society Portal. https://www.environmentandsociety.org/tools/keywords/roundup-ready-first-widely-used-genetically-modified-crop

International Agency for Research on Cancer | World Health Organization (WHO). (2017). Some organophosphate insecticides and herbicides (Volume 112 - IARC MONOGRAPHS ON THE EVALUATION OF CARCINOGENIC RISKS TO HUMANS) [Report]. IARC Monographs. https://monographs.iarc.who.int/wp-content/uploads/2018/07/mono112.pdf

International Agency for Research on Cancer. (2021). Agents Classified by the IARC Monographs, Volumes 1–129. Monographs IARC World Health Organization. Retrieved October 31, 2021, from https://monographs.iarc.who.int/agents-classified-by-the-iarc/

Jalsenjak, B. (2019). Ethical absolutism v ethical relativism. In S. Idowu, R. Schmidpeter, N. Capaldi, L. Zu, M. Del Baldo, & R. Abreu (Eds.), Encyclopedia of sustainable management. Springer International Publishing. https://doi.org/10.1007/978-3-030-02006-4_116-1

Katz, E., & Stark, O. (1986). Labor migration and risk aversion in less developed countries. Journal of Labor Economics, 4(1), 134–149. https://doi.org/10.1086/298097

Lotz, L. P., Christensen, S., Cloutier, D., Quintanilla, C., Legere, A., Lemieux, C., Lutman, P. W., Iglesias, A., Salonen, J., Sattin, M., Stigliani, L., & Tei, F. (1996). Prediction of the competitive effects of weeds on crop yields based on the relative leaf area of weeds. Weed Research, 36(1), 93–101. https://doi.org/10.1111/j.1365-3180.1996.tb01805.x

Mesnage, R., & Antoniou, M. N. (2017). Facts and fallacies in the debate on glyphosate toxicity. Frontiers in Public Health, 5. https://doi.org/10.3389/fpubh.2017.00316

Mesnage, R., Defarge, N., Spiroux de Vendômois, J., & Séralini, G.-E. (2014). Major pesticides are more toxic to human cells than their declared active principles. BioMed Research International, 2014, 1–8. https://doi.org/10.1155/2014/179691

Myers, J., Antoniou, M. N., Blumberg, B., Carroll, L., Colborn, T., Everett, L. G., Hansen, M., Landrigan, P. J., Lanphear, B. P., Mesnage, R., Vandenberg, L. N., Vom Saal, F. S., Welshons, W. V., & Benbrook, C. M. (2016). Concerns over use of glyphosate-based herbicides and risks associated with exposures: A consensus statement. Environmental Health, 15(1). https://doi.org/10.1186/s12940-016-0117-0

Norberg-Hodge, H., Merrifield, T., & Gorelick, S. (2002). Bringing the food economy home: Local alternatives to global agribusiness. Zed Books.

Portier, C. J., Armstrong, B. K., Baguley, B. C., Baur, X., Belyaev, I., Bellé, R., Belpoggi, F., Biggeri, A., Bosland, M. C., Bruzzi, P., Budnik, L., Bugge, M. D., Burns, K., Calaf, G. M., Carpenter, D. O., Carpenter, H. M., López-Carrillo, L., Clapp, R., Cocco, P.,...Zhou, S.-F. (2016). Differences in the carcinogenic evaluation of glyphosate between the international agency for research on cancer (IARC) and the European food safety authority (EFSA). Journal of Epidemiology and Community Health, 70(8), 741–745. https://doi.org/10.1136/jech-2015-207005

PR Newswire. (July 31, 2018). Research report on China's glyphosate industry (2018-2022). Cision PR Newswire. https://www.prnewswire.com/news-releases/research-report-on-chinas-glyphosate-industry-2018-2022-300689149.html

Reuters. (2021, August 10). Bayer loses third appeals case over glyphosate weedkiller. Reuters. https://www.reuters.com/business/healthcare-pharmaceuticals/bayer-loses-third-appeals-case-over-glyphosate-weedkiller-2021-08-10/

Rew, L. J., Lehnhoff, E. A., & Maxwell, B. D. (2007). Non-indigenous species management using a population prioritization framework. Canadian Journal of Plant Science, 87(5), 1029–1036. https://doi.org/10.4141/cjps07121

Robinson, G. M. (2018). Globalization of agriculture. Annual Review of Resource Economics, 10(1), 133–160. https://doi.org/10.1146/annurev-resource-100517-023303

Robinson, G. M., & Carson, D. A. (2015). Handbook on the globalisation of agriculture. Edward Elgar Publishing.

Roundup. (n.d.). Where there’s a weed there’s a way. https://www.roundup.com/en-us

Samsel, A., & Seneff, S. (2013). Glyphosate, pathways to modern diseases ii: Celiac sprue and gluten intolerance. Interdisciplinary Toxicology, 6(4), 159–184. https://doi.org/10.2478/intox-2013-0026

Sigrimis, N., Antsaklis, P., & Groumpos, P. P. (2001). Advances in control of agriculture and the environment. IEEE Control Systems, 21(5), 8–12. https://doi.org/10.1109/37.954516

Skurski, T. C., Maxwell, B. D., & Rew, L. J. (2013). Ecological tradeoffs in non-native plant management. Biological Conservation, 159, 292–302. https://doi.org/10.1016/j.biocon.2012.10.017

Sokolove Law. (n.d.). Roundup® Lawsuit. Retrieved October 31, 2021, from https://www.sokolovelaw.com/product-liability/monsanto-roundup/

Stark, O. (1984). Rural-to-urban migration in IDCS: A relative deprivation approach. Economic Development and Cultural Change, 32(3), 475–486. https://doi.org/10.1086/451401

Statista. (2016). Glyphosate use worldwide from 1994 to 2014 (in 1,000 kilograms) [Data set]. https://www.statista.com/statistics/567250/glyphosate-use-worldwide/

Sung, J. (2018). The fourth industrial revolution and precision agriculture. In Automation in agriculture - securing food supplies for future generations. InTech. https://doi.org/10.5772/intechopen.71582

Székács, A., & Darvas, B. (2011). Forty years with glyphosate. In M. N. Hasaneen (Ed.), Herbicides: Properties, Synthesis, and Control of Weeds (pp. 247–284). InTech.

Tarazona, J. V., Court-Marques, D., Tiramani, M., Reich, H., Pfeil, R., Istace, F., & Crivellente, F. (2017). Glyphosate toxicity and carcinogenicity: A review of the scientific basis of the European union assessment and its differences with IARC. Archives of Toxicology, 91(8), 2723–2743. https://doi.org/10.1007/s00204-017-1962-5

Tasman, J. (March 13, 2017). GMO building blocks: 5 of 17 – could glyphosate be another case like DDT or Thalidomide? WordPress (GMO Building Blocks). http://fafdl.org/gmobb/5-of-17-could-glyphosate-be-another-case-like-ddt-or-thalidomide/

The Ethics Centre. (2016a, February 15). Ethics Explainer: Consequentialism. https://ethics.org.au/ethics-explainer-consequentialism/

The Ethics Centre. (2016b, February 18). Ethics Explainer: Deontology. https://ethics.org.au/ethics-explainer-deontology/

The Washington Post. (2017, November 10). UPDATE 2-Large U.S. farm study finds no cancer link to Monsanto weedkiller. The Washington Post. Retrieved October 31, 2021, from https://www.washingtonpost.com/national/health-science/study-finds-no-firm-link-between-chemical-in-popular-weedkiller-and-cancer/2017/11/10/1f8096c0-c578-11e7-aae0-cb18a8c29c65_story.html

Travlos, I., Cheimona, N., & Bilalis, D. (2017). Glyphosate efficacy of different salt formulations and adjuvant additives on various weeds. Agronomy, 7(3), 60. https://doi.org/10.3390/agronomy7030060

United Nations Educational, Scientific, and Cultural Organization. (2017). Culture for sustainable development. Unesco.org. Retrieved May 30, 2021, from http://www.unesco.org/new/en/culture/themes/culture-and-development/the-future-we-want-the-role-of-culture/globalization-and-culture/#:~:text=While%20this%20phenomenon%20promotes%20the,identity%2C%20exclusion%20and%20even%20conflict.

United States Environmental Protection Agency. (n.d.). CADDIS Volume 2 | Herbicides. EPA.gov/Caddis Volume 2. https://www.epa.gov/caddis-vol2/caddis-volume-2-sources-stressors-responses-herbicides

Uri, N. D. (2000). Perceptions on the use of no-till farming in production agriculture in the united states: An analysis of survey results. Agriculture, Ecosystems & Environment, 77(3), 263–266. https://doi.org/10.1016/s0167-8809(99)00085-7

US Environmental Protection Agency. (n.d.). Glyphosate. Ingredients used in pesticide products. https://www.epa.gov/ingredients-used-pesticide-products/glyphosate

Washington State University. (2015, July 23). U.S. breast milk is glyphosate free: Study is first independently verified look for the presence of Roundup ingredient in human milk. Science Daily. https://www.sciencedaily.com/releases/2015/07/150723133120.htm

Wechsler, S. J., Smith, D., McFadden, J., Dodson, L., & Williamson, S. (2019, October 1). The use of genetically engineered dicamba-tolerant soybean seeds has increased quickly, benefiting adopters but damaging crops in some fields. U.S. Department of Agriculture (USDA) economic research service: Crop and livestock practices. https://www.ers.usda.gov/amber-waves/2019/october/the-use-of-genetically-engineered-dicamba-tolerant-soybean-seeds-has-increased-quickly-benefiting-adopters-but-damaging-crops-in-some-fields/

Yenduri, A., & Sumant, O. (2019). Herbicides Market [Data set]. Allied Market Research. https://www.alliedmarketresearch.com/herbicides-market

Zacune, J. (March 2012). Combatting Monsanto Grassroots resistance to the corporate power of agribusiness in the era of the ‘green economy’ and a changing climate (R. Hall, Ed.). La Via Campesina. https://viacampesina.org/en/wp-content/uploads/sites/2/2012/04/Monsanto-Publication-EN-Final-Version.pdf

Zhang, L., Rana, I., Shaffer, R. M., Taioli, E., & Sheppard, L. (2019). Exposure to glyphosate-based herbicides and risk for non-Hodgkin lymphoma: A meta-analysis and supporting evidence. Mutation Research/Reviews in Mutation Research, 781, 186–206. https://doi.org/10.1016/j.mrrev.2019.02.001

Zhao, X., Liu, S.-L., Pu, C., Zhang, X.-Q., Xue, J.-F., Ren, Y.-X., Zhao, X.-L., Chen, F., Lal, R., & Zhang, H.-L. (2017). Crop yields under no-till farming in china: A meta-analysis. European Journal of Agronomy, 84, 67–75. https://doi.org/10.1016/j.eja.2016.11.009

DOI: https://doi.org/10.5296/csbm.v9i1.19457


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