Nitric Oxide in Health and Physical Performance: Considering the Molecule 2 Nitrooxy Ethyl 2 Amino 3 Methylbutanoate

Abstract

Nitric oxide (NO^∙) is an important signaling molecule that has received considerable attention in recent years for its beneficial impact on a variety of health related outcomes. The effects range from improving various aspects of circulatory health to aiding exercise performance. Although NO^∙ is produced naturally within the body, methods have been proposed to increase circulating NO^∙ within humans. Most notably, the performance of regular exercise, the use of pharmaceutical agents, and the use of nutritional ingredients has been studied. A newly developed molecule known as 2 nitrooxy ethyl 2 amino 3 methylbutanoate (VEEN™) is now being studied as a next generation NO^∙ agent. This paper discusses the importance of NO^∙ in human health, with a particular focus on methods to increase NO^∙. Attention is given to VEEN™, highlighting the studies performed to date using this molecule.